To have adequate immune response during wound healing, total lymphocyte count should be above what value?

• A. 1000
• B. 2500
• C. 2000
• D. 1500

Answer: (D)

Adequate immune response during wound healing relies on enough circulating lymphocytes to coordinate defense and tissue repair. Lymphocytes, including T cells, B cells, and natural killer cells, drive the immune reaction that fights infection and helps regulate the inflammatory and proliferative phases of healing. They secrete cytokines that activate macrophages, guide neutrophil function, and support fibroblast activity for collagen deposition and tissue remodeling. When the lymphocyte pool is sufficiently large, these processes proceed efficiently, helping prevent infection and promote timely healing. If lymphocyte levels fall below the mid-normal range, the immune response becomes blunted, increasing infection risk and delaying wound repair. Therefore, the practical threshold clinicians and exams reference is being above that mid-normal level, which supports an adequate immune response during wound healing.