What should also be used when using PMMA beads?

• A. Sterile saline flush
• B. No drainage management
• C. A drain
• D. Antibiotic irrigation

Answer: (C)

Placing PMMA beads for local antibiotic delivery creates a space that can readily accumulate fluid after debridement. A drain is used to continuously evacuate this fluid, prevent seroma or hematoma formation, and reduce the risk of ongoing infection. By providing a path for drainage, a drain helps maintain an environment that supports healing and allows monitoring of wound output for signs of persistent infection. The beads themselves deliver high local antibiotic concentrations, and adding a drain ensures that the surrounding tissues don’t fill with fluid that could compromise healing or bead efficacy.