Which component is associated with ester-type local anesthetics and can lead to allergic reactions?

Unlock all questions

This demo includes only 20 questions. Upgrade to access hundreds of questions, flashcards, exam simulations, and disable ads.

Full question bankExam simulationsFlashcards
From $24.99Unlock all

Prepare for the ABFAS Boards with our comprehensive quiz on Rearfoot and Forefoot topics. Dive into multiple choice questions, get detailed explanations, and boost your confidence for success!

Multiple Choice

Which component is associated with ester-type local anesthetics and can lead to allergic reactions?

Explanation:
Ester-type local anesthetics are rapidly broken down in the body to para-aminobenzoic acid (PABA) plus an alcohol. PABA can act as an allergen in some individuals, making it a classic source of hypersensitivity reactions associated with ester-type anesthetics. That’s why the component tied to ester LAs and capable of triggering allergies is PABA. While the drugs themselves (like benzocaine or tetracaine) are ester anesthetics, the allergic reactions are most commonly linked to the metabolite PABA. Lidocaine, an amide anesthetic, is not metabolized to PABA and is less typically involved in this specific allergen pathway.

Ester-type local anesthetics are rapidly broken down in the body to para-aminobenzoic acid (PABA) plus an alcohol. PABA can act as an allergen in some individuals, making it a classic source of hypersensitivity reactions associated with ester-type anesthetics. That’s why the component tied to ester LAs and capable of triggering allergies is PABA. While the drugs themselves (like benzocaine or tetracaine) are ester anesthetics, the allergic reactions are most commonly linked to the metabolite PABA. Lidocaine, an amide anesthetic, is not metabolized to PABA and is less typically involved in this specific allergen pathway.

More Multiple Choice Questions
Subscribe

Get the latest from Examzify

You can unsubscribe at any time. Read our privacy policy