Which local anesthetic is least likely to cause methemoglobinemia?

Unlock all questions

This demo includes only 20 questions. Upgrade to access hundreds of questions, flashcards, exam simulations, and disable ads.

Full question bankExam simulationsFlashcards
From $24.99Unlock all

Prepare for the ABFAS Boards with our comprehensive quiz on Rearfoot and Forefoot topics. Dive into multiple choice questions, get detailed explanations, and boost your confidence for success!

Multiple Choice

Which local anesthetic is least likely to cause methemoglobinemia?

Explanation:
Methemoglobinemia risk with local anesthetics depends on how they are metabolized and whether oxidative metabolites are produced. Prilocaine is well known to generate an oxidative metabolite (o-toluidine) that raises methemoglobin levels, and benzocaine—especially in topical forms—has a documented association as well. Lidocaine can cause methemoglobinemia, but it is much less common. Bupivacaine (Marcaine) has the lowest risk among these because it does not produce the same oxidizing metabolites in clinically relevant amounts. So, the local anesthetic least likely to cause methemoglobinemia is Marcaine.

Methemoglobinemia risk with local anesthetics depends on how they are metabolized and whether oxidative metabolites are produced. Prilocaine is well known to generate an oxidative metabolite (o-toluidine) that raises methemoglobin levels, and benzocaine—especially in topical forms—has a documented association as well. Lidocaine can cause methemoglobinemia, but it is much less common. Bupivacaine (Marcaine) has the lowest risk among these because it does not produce the same oxidizing metabolites in clinically relevant amounts. So, the local anesthetic least likely to cause methemoglobinemia is Marcaine.

More Multiple Choice Questions
Subscribe

Get the latest from Examzify

You can unsubscribe at any time. Read our privacy policy